Biotek elx 405 manual




















Volume Range. Wash Cycles. Auto switching module for up to 4 buffers option. Supply bottle. Dispense Precision. Residual Volume. Wash Speed. Flow Rates. High flow to low flow. Optimized rates for cell assays. Vacuum Filtration. Selectable: Approximate final at 30 seconds:. Lowest: mmHg. Low: mmHg. Medium: mmHg. High: mmHg. Highest: mmHg. Vacuum filtration time range: 5 to seconds. Our technicians decontaminate and clean equipment upon arrival at our facility and upon your purchase to create a neutral environment for your labs use.

Preliminary testing is then conducted on our equipment to identify potential defects. Any parts known to fail or malfunction on the piece of equipment are removed and replaced to insure the extended lifetime of your equipment. Any necessary preventative maintenance is performed alongside repairs, so your purchase will be ready to go as soon as it arrives.

All of the electronics and boards are tested for proper function and response by our industry trained technicians. Any electronic deficiencies detected are immediately repaired.

Final testing cycles ensure your equipment performs fully at manufacturer specifications, guaranteeing you receive a properly working product ready for use. Once we finish our rigorous testing and decontamination procedures, your order will be packaged to best protect it during shipment and will include delivery insurance.

If detergent was used, wipe the components with a cloth moistened with water. Use a clean, dry cloth to dry the components. To replace the carrier, line up the pin on the underside of the carrier with the slot on the carrier transport rail. Snap the two carrier rail guides onto the rail. The pin should sit in the slot. Cleaning the Carrier Transport Arm Select, Select CW, and HT Models For troubleshooting purposes, it may be necessary to disassemble and clean the spring-loaded carrier transport arm that allows the Select, Select CW, and HT models to move forward and back along the y-axis when washing well plates.

If reagent has spilled and dried on the stainless steel shaft of the arm, it may interfere with carrier movement. Cleaning the arm will resolve the problem. The transport arm is noted with an arrow in the photo above. As shown in the photo, the arm fits into the left side of the plate carrier. Follow the instructions on the next two pages for removing, cleaning, and reassembling the transport arm. Turn the carrier over and lay it face down to expose the two screws that hold the arm in place in the carrier noted with an arrow in the photo below.

Take note of the orientation of the arm to the plate carrier as it is turned upside down. Be sure to reassemble the components properly. Reassemble the carrier: Slide the arm back into the open end of the plate carrier. Squeeze the arm spring against the carrier to expose the openings for the screws and washers, and reinstall them.

Cleaning the Manifold, Mist Shield, and Tubing Regular rinsing helps to keep the manifold clean, the aspiration and dispense tubes clear, and it increases the life of the tubing.

If you suspect a particular problem is related to the manifold for example, clogged tubes can result in poor or uneven aspiration or dispensing , you should perform a thorough cleaning of the dispense and aspirate tubes and channels.

To clean the manifold, mist shield, and tubing: 1. Connect an empty supply bottle and prime the washer until the tubing is empty. Set the vacuum, fluid, and flow detection sensors back to YES. Moisten a lint-free disposable towel with water, or with water and mild detergent.

Do not soak the cloth. Remove the mist shield if it is attached see Figure 16 in Chapter 2, Installation. Wipe the inside and outside surfaces of the mist shield with the towel. Wipe the top surface of the instrument base, and all exposed surfaces of the instrument.

Hold the two manifolds together as a single unit when removing or replacing. Carefully remove the manifold s and end plates. Using a soft-bristled brush, thoroughly clean the outside of the manifold s. Flush hot water through the cross channels. Rinse the manifold with deionized or distilled water. Check to see if water comes out of all dispense and aspirate tubes.

If not, soak the manifold in hot, soapy water and repeat. When reinstalling the manifold, only tighten the screw-washer-spring assembly that holds it in place until you feel the mechanical stop. You will damage the instrument if you continue tightening past this point, and will void your warranty. When satisfied, reassemble the manifold and end plates, making sure that the two o-rings are in place prior to reassembly. Do not overtighten the manifold screws. Re-attach the mist shield; finger-tighten the two thumbscrews use no tools.

Reconnect the power cable and turn on the washer. Watch for leaks. If fluid leaks out of the back of the instrument, firmly seat the tubing. If fluid leaks from the manifold, try disassembling and carefully reassembling. Replace the o-rings on an annual basis. Replace the 12 or 24 channel-end seals rubber plugs if they show signs of cracking or drying out.

Do not try to remove the ultrasonic cleaner! Only Bio-Tek authorized service personnel should remove the cleaner for maintenance or repair. Do not put your fingers in the bath! Ultrasonic energy causes cavitation forces within the water bath, which in turn cause tiny vapor bubbles to be created.

The formation and subsequent collapse of these bubbles is the mechanism that cleans manifold tubes submerged in the bath. The cleaner consists of a stainless steel reservoir with an ultrasonic transducer bonded to the bottom of the reservoir. The reservoir is mounted on the washer in the same position as the priming trough in other models. Only Bio-Tek authorized service personnel should remove the ultrasonic cleaner for maintenance or repair.

Run one or more loops in the cleaning program for 30 minutes in each loop. Follow with a rinse loop using deionized water to remove the detergent from the system, or with a wash buffer to leave the instrument primed and ready for use. Prepare the waste and supply bottles Empty the waste bottle. Ensure that there is a sufficient volume of deionized water and detergent in the supply bottle s : An AUTOCLEAN program initially primes the system with ml of fluid from the supply bottle specified for Loop 1; each cleaning loop fills the reservoir with approximately 93 ml of fluid.

Priming with ml is always done for each successive loop in models without the valve module, and in models with the valve module, if the valve selection changes between loops. The program begins with a priming sequence.

When priming is complete, the manifold lowers into the reservoir, the washer dispenses approximately 93 ml of fluid, and cleaning LOOP 01 begins. When the loop is complete, the washer aspirates the fluid from the reservoir. If another loop is specified in the program, the washer is primed only if valve selection changes or if operating without the valve module , fluid is dispensed, and the next loop begins.

This process is repeated until all loops are complete. Cleaning the Fluid Inlet Filter Warning! Periodically clean the fluid inlet filter PN that is located next to the vacuum port on the rear panel of the instrument. To clean the filter: 1. Decontaminate the Washer Any laboratory instrument that has been used for research or clinical analysis is considered a biohazard and requires decontamination prior to handling.

Decontamination minimizes the risk to all who come into contact with the instrument during shipping, handling, and servicing. Decontamination is required by the U. Persons performing the decontamination process must be familiar with the basic setup and operation of the instrument. The recommended frequency for decontamination is at least monthly, and before shipment of the instrument to Bio-Tek for calibration or repair.

Each laboratory must ensure that decontamination procedures are adequate for the Biohazard s they handle. Turn off and unplug the instrument for all decontamination operations. Wear prophylactic gloves when handling contaminated instruments. Eating and drinking while decontaminating instruments is not advised. Wear protective gloves when performing the decontamination procedure. For shipment of the instrument to Bio-Tek for calibration or repair, decontaminate both manifolds. The bleach solution is caustic; wear gloves and eye protection when handling this solution.

Be sure to check the percent NaClO of the bleach you are using; this information is printed on the side of the bottle. Prepare an aqueous solution of 0. Isopropyl alcohol is not recommended for removing proteins such as bovine serum albumin. Wipe the keypad do not soak. Wipe again with a clean cloth moistened with deionized or distilled water. Dry immediately with a clean, dry cloth. Wipe the inside and outside surfaces of the mist shield.

Wait 20 minutes. Moisten a cloth with DI or distilled water. Discard the used gloves and cloths using a Biohazard trash bag and an approved Biohazard container. This program flushes and soaks the supply tubing and manifold with disinfectant, then flushes the system with rinse, and finally purges the system of fluid.

These Prime programs can be edited for optimum cleaning. Refer to the charts in the Prime Programs section of this chapter for a list of default parameters and to Chapter 3, Operation, for instructions on editing these parameters. Two supply bottles are required for this procedure: one for disinfectant, and one for rinse. While this program is running, you will need to periodically check the display panel and follow the instructions. Remove the mist shield, if it is attached: Using your fingers, loosen the two thumbscrews on the shield use no tools.

Lift the shield off the two posts. Refer to Decon Procedure for External Surfaces of the Instrument on page for decontamination of the mist shield. Hold the two manifolds and end plates together as a single unit when removing or replacing.

Remove the manifold s and end plates. Reassemble the manifold and end plates, making sure that the two o-rings are in place prior to reassembly. Do not overtighten the manifold.

Re-attach the mist shield: Align the mist shield with the washer so it is resting on top of the two posts, and the two thumbscrew holes in the shield are lined up with the two holes in the front base of the washer. Insert the two thumbscrews and finger-tighten only use no tools. Prime program. Discard the used gloves and cloths using a Biohazard trash bag and an. Prepare for Storage or Shipment Before the washer is shipped or stored, it should be rinsed and soaked with disinfectant and then purged of all fluid.

Perform these steps when leaving the washer unused for a long period of time. These prime programs can be edited for optimum cleaning. Refer to the charts in the Prime Programs section of this chapter for a list of default Prime program parameters and to Chapter 3, Operation, for instructions on editing these parameters. Three supply bottles are required for this procedure: one for disinfectant, one for rinse, and one for air. If the washer is equipped with the external valve module, connect the supply bottles this way: Valve A: Disinfectant bottle Valve B: Rinse solution bottle Valve C: Empty bottle.

Store the washer on a flat surface that is relatively free of vibration, in a dust-free and particle-free environment. Protect the washer from temperature extremes that can cause condensation within the unit and from corrosive fumes and vapors. Replace Components Replacing the O-Rings and Channel-End Seals For optimal performance and to extend the life of the washer, replace the manifold o-rings once a year and replace the 12 or 24 rubber plugs seals on the channel ends if they show signs of cracking or drying out.

Order the replacement o-rings and seals from Bio-Tek see page You must remove the manifold to change the seals, so these tasks work best in conjunction with the Cleaning the Manifold, Mist Shield, and Tubing procedure on page Replacing the O-Rings After completing Step 9 of the procedure on page 1. Using your fingers or an appropriate tool, such as a very small, flat screwdriver, remove the two o-rings that are exposed when the manifold is removed.

If you are not replacing the channel end-seals at this time, reinstall the manifold. Caution: When reinstalling the manifold, only tighten the screw-washer-spring assembly that holds it in place until you feel the mechanical stop. You will damage the instrument if you continue tightening past this point. If the channel-end seals do not need to be replaced, they should be washed with mild detergent or alcohol.

See Figure 29 on the following page. The manifold end plate sits in front of the manifold and holds the screws, washers, and springs that hold the manifold in place. The manifold end plate has markings to indicate its position relative to the manifold, e. Using an appropriate tool, such as a very small, flat screwdriver or a paper clip, remove the seals from the manifold end plate.

Caution: Do not grease any parts of this mechanism. Lubricate the seals and the bored holes with alcohol to assist with reinsertion. Make sure the seals sit firmly in the bored holes in the manifold end plate. When all of the seals are in place, reinstall the manifold end plates and the manifold.

For washers equipped with the optional valve module, instrument verification includes Dispense Precision tests for the valve module. The System Self Test verifies system components, such as the vacuum, manifold, and carrier positioning. The Checksum Test verifies the basecode software against internal checksum values to ensure that no corruption has occurred.

If the Checksum Test is run manually, part number and version information is displayed for the software on the instrument. The lower the residuals per well, the better the evacuation efficiency of the washer. Dispense Precision, Valve Module. The Dispense Precision Test for the external valve module measures the variability of volumes dispensed from tube to tube across the manifold, when the washer is used with the valve module.

Verification Schedule The following schedule defines the factory-recommended intervals for verification tests for a washer used two to five days a week. The schedule assumes that the washer is properly maintained as outlined in Chapter 4, Preventative Maintenance. Recommended Instrument Verification Schedule. The risk factors associated with your assays may require that the Operational and Performance Qualification procedures be performed more or less frequently than shown above.

Note: An instrument qualification package PN for the washer is available for purchase. Installation Qualification IQ Installation Qualification confirms that the washer and its components have been. The recommended IQ procedure consists of setting up the instrument as described in Chapter 2, Installation and then performing the System Self-Test and the Checksum test.

The successful completion of the IQ procedure verifies that the instrument is installed correctly. The Operational Qualification procedure should be performed immediately following the successful IQ see below. Operational Qualification OQ Operational Qualification confirms that the washer operates according to. You should not use the data obtained from the first assay that utilizes the washer until you have confirmed that the package insert criteria have been met.

The OQ procedure should be performed initially before first use and then routinely; the recommended interval is annually. It should also be performed after any major repair or upgrade to the hardware or software. Although out-of-tolerance failures will be detected by the OQ tests, results should be compared with those from the monthly Performance Qualification tests and previous OQ tests to monitor for trends.

The successful completion of the OQ procedure, in combination with results that are comparable to previous PQ and OQ tests, confirms that the washer is performing consistently over time. Performance Qualification PQ Performance Qualification confirms that the washer consistently meets the.

These tests should be performed routinely; the recommended interval is monthly. This frequency may be adjusted depending on the trends observed over time. The successful completion of the PQ procedure confirms that the washer is performing consistently under normal operating conditions.

The System Self Test and Checksum Test are performed automatically whenever the washer is powered on. System Self Test The System Self Test checks the vacuum when run manually , manifold, and manifold-to-carrier positioning.

For the Magna, a magnetic carrier test is also performed. To run the System Self Test:. If this happens, write down the error code and then press the Stop key on the keypad to stop the beeping. Look up the error code in Appendix B, Error Codes, to determine its cause. Checksum Test The Checksum Test compares the on-board software with an internally recorded checksum value to ensure the program has not become corrupted.

To run the Checksum Test:. The first screen will display the onboard basecode software part number, version number, and checksum: xxx Version x. After a few seconds, a second screen will display the assay software part number and version number: xxx Version x. The Main Menu will be displayed after the test is finished.

If you need to provide the Checksum information to TAC: Since the above screens are displayed only briefly, you may have to run the Checksum Test a few times to record all of the required information.

Liquid Tests HT models with the accessory tube manifold: Ensure that the washer is configured for operation with the correct manifold 96 or refer to Manifold Selection in Chapter 3, Operation. Failure to set the correct manifold type in the software before operating the washer may damage the manifold and void your warranty.

Evacuation Efficiency Test The Evacuation Efficiency test measures the residual volume mean residual weight per well after the aspiration aspect of plate washing. The lower the residual per well, the better the evacuation efficiency of the washer. A known solution is dispensed into all wells of a previously weighed microplate. The aspiration program is run and the plate is reweighed in order to calculate the total residual fluid based on the weight difference. The total residual fluid weight is divided by 96 or as appropriate to obtain the mean residual weight.

Buffer is then pipetted to all wells to bring the volume of fluid to a consistent measurement level. The optical density of each well is measured at nm and the background at nm is subtracted to account for scratches on the plate or particulates in a well.

Dispense Precision Test The Dispense Precision Test measures the variability of the volumes dispensed from tube to tube across the manifold. In this test, a blue dye solution is dispensed into a microplate.

The optical density of each well is measured at nm and the background at nm is subtracted to account for scratches on the plate or particulates in the well. The average error percentage is calculated and the amount dispensed to each well is calculated. Valve Module Test The Dispense Precision test is conducted for the external valve module to ensure that each valve A, B, C, D in the module is calibrated to deliver the same volume of fluid. Which Tests to Perform?

Which tests you will perform depend on the washer model, which manifold type is installed on it, and whether or not the washer is equipped with the external valve module. Please refer to the chart below to determine which tests to perform. These volumes are sufficient for performing the standard and supplemental Evacuation Efficiency tests, plus the Dispense Precision test.

In most cases, enough fluid will be left over to re-run a test, if necessary. If you will be performing the annual OQ with the external valve module, you will need several additional liters of deionized water. You may use your own buffer solution in place of Solution 1. If any tests fail using your own buffer, however, retry the tests using the suggested solutions. Using pure DI water in place of Solution 1 is not recommended and will likely result in the failure of the unit to meet specifications.

See page for a list of required materials. Fill a supply bottle with two liters of deionized water. This program evacuates all of the wells, leaving a small amount of residual fluid. When the program is finished, remove the plate and weigh it immediately, because evaporation will affect the results.

This is the Total Residual Weight, in grams. Visually inspect the plate and note if any wells appear to have considerably more liquid in them than others.

Using the Evacuation Efficiency Test Worksheet on page , perform initial data reduction: a. If the Mean Residual Weight is greater than 0. Troubleshoot as follows:. See Chapter 3, Operation, for instructions on copying and editing programs and modifying the abovementioned parameters. After making this change, retry the test using a clean, dry microplate. See Chapter 4, Preventive Maintenance for complete instructions. When finished, retry the test using a clean, dry microplate.

Repeat steps 2 through 7 of the previous test, using Solution 2 for the dispense fluid. Be sure to recalculate the Mean Residual Weight. Shake the plate to get uniform distribution of the remaining dye in each well. Set it to NO. Read the plate in an optical reader blank on air , using the dual-wavelength method nm - nm , then print or export the results. Using the Evacuation Efficiency Test Worksheet on page , perform data reduction: a. Calculate the sum of the OD values for all 96 wells, then divide by 96 to determine the Mean OD for the plate.

If one or more wells has a Residual Weight greater than 0. When finished, retry the test. If the problem appears to be related to a particular region, edge, or corner of the plate, review the alignment and flatness of the plate on the carrier. Please do not adjust the carrier adjustment screws! Contact your Bio-Tek dealer if you suspect an alignment problem. For additional suggestions, see Appendix A, Troubleshooting. If the test continues to fail, contact Bio-Tek Instruments.

It does not evacuate the solution. When the program is finished, carefully remove the plate. Using the Dispense Precision Test Worksheet on page , perform data reduction: a. Calculate the Standard Deviation. When finished, re-prime the washer and retry the test.

Fill the supply bottle for Valve A with two liters of deionized water. Read the plate in an optical reader blank on air , using the dualwavelength method nm — nm , then print or export the results. The routine test for Valve A see previous page must pass before the annual test for Valves A-D can be performed. Fill each of the supply bottles connected to Valves A, B, C, and D with three liters ml of deionized water.

Place the bottles on a surface level with the washer, i. It does not evacuate the wells. When the program is finished, carefully remove the plate and weigh it. This is the Total Dispense Weight in grams. The weight should be If the weight falls outside this range, contact Bio-Tek. If the weight falls below this range, the fluid inlet filter could be clogged, or the valve may be contaminated with fungi or proteins. The valve should be cleaned using an appropriate enzyme, alcohol, or a diluted bleach solution, depending on the contaminant.

After cleaning the fluid inlet filter or valve and tubing, retry the test. If the test continues to fail, contact Bio-Tek. You will then edit the copy when performing step 4. To copy the test program:. When finished entering the name, press the Enter key. Read the plate in an optical reader blank on air , using the dualwavelength method nm - nm , then print or export the results. Calculate the sum of the OD values for all wells, then divide by to determine the Mean OD for the plate.

For additional suggestions, refer to Appendix A, Troubleshooting. Using the appropriate Dispense Precision Test Worksheet on page , perform data reduction: a. When finished, reprime the washer and retry the test.

This appendix lists problems that you may experience with the washer, and suggests possible solutions for these problems. This appendix offers the following information to help resolve these problems.

The Troubleshooting Checklist below is a concise summary of possible causes for many of the problems that may occur during operation of the washer. The Troubleshooting Charts on the following pages provide detailed lists of problems, their possible causes, and possible solutions. Troubleshooting Checklist Periodic inspection of the washer, tubing, and bottles for the possible causes listed below may help to eliminate many of the problems listed on the following pages.

Check for the following:. Replace fuse PN Increase vacuum dissipation delay refer to the section on Vacuum Dissipation Delay in Ch. Ensure that the vacuum pump accessory cable is plugged into the vacuum pump accessory outlet on the back of the washer, and not into a wall outlet. See Ch. Turn washer off, wait at least 15 seconds, then turn back on. HT models with the accessory tube dual manifold including Select models upgraded to HT models : Ensure that the washer is configured for the installed manifold tube or tube.

See Manifold Selection in Ch. Firmly seat the waste bottle covers. Ensure tubing is connected properly. Check all external tubing for kinks or clogs. If you are using an in-line vacuum filter, the filter may need to be replaced. If the vacuum pump is on, remove the vacuum pump tubing from the back of the washer while the pump is on. Bio-Tek offers a high flow pump for those and well assays using only water for the wash fluid. Contact Bio-Tek for more information. Check aspiration height, waste system for leaks, waste bottle caps, tubing for kinks, and in-line filter for clogs.

Check to see if the microplate is not level or if the waste valve of the valve module is touching the bench. Clean the aspiration tubes with a stylus. Try these changes in this order and in combination if necessary: 1. Enable crosswise aspiration. Increase aspiration time to ms. Slow aspiration speed to 1 or 2. Reseat microplate in carrier or strips in holder.

Try a different microplate or strip holder. If the problem is unresolved, the carrier may have to be realigned. Other options include decreasing the aspiration rate or adding a delay on the final aspiration. Note: Monthly performance of the Evacuation Efficiency test is recommended to verify that the residual volume per well after evacuation aspiration meets the specified criteria. Clean the fluid inlet filter. Straighten or connect supply tube.

Make sure the end is cut; see General Usage Guidelines, Ch. Fill bottles with appropriate fluid. Ensure bottles are clean and do not contain particles or organic material. Run a Prime program using the following volumes; do not use the AutoPrime program for the initial prime:. All models except Select CW: ml Prime Volume when all the lines are empty or when changing fluids.

Run a Prime program using the following volumes: All models except Select CW: ml Prime Volume when all the lines are empty or when changing fluids. Make sure valve module cable is plugged into the valve control port on the back of the washer. Dispense height too high. The aspirate tubes are too many steps above the microwells to prevent overflow. Aspiration tubes hit bottom of trough during Prime or Maintenance. Note: Monthly performance of the Dispense Precision test is recommended to measure the variability of volumes dispensed from tube to tube across the manifold.

Firmly seat the waste bottle covers; ensure tubing is connected properly. An in-line vacuum filter may need to be replaced. When the program begins, you should be able to hear the vacuum pump turn on. If the vacuum pump turns on, remove the vacuum tubing from the back of the washer while the pump is on and put your finger over the port. Run a prime program using the following minimum Prime Volumes; do not use the AutoPrime program for the initial prime: All models except Select CW, Without the valve module, ml Prime Volume when all the lines are empty or when changing fluids.

With the valve module, ml Prime Volume when all the lines are empty or when changing fluids. Dispense flow rate too low. Microplate aspiration height adjustment too high or too low. Replace individual seals at the front of the manifold, or o-rings at the rear of the manifold see Cleaning the Manifold in Ch.

Replace o-rings on washer manifold inlet fittings. Check waste connector tubes; make sure they are properly connected to the manifold. If you are using an in-line vacuum filter, check the filter for clogging, and replace if necessary.

Check seal of waste bottle covers. Check for air leaks in the waste tubing and bottles. Check orientation of microplate; A1 should be in the left rear corner of the plate carrier as you face the front of the instrument.

Check for and remove any obstructions. HT models with the accessory 96tube manifold including Select models upgraded to HT models : Ensure that the washer is configured for the installed manifold tube or tube. If an error is displayed, refer to Appendix A, Troubleshooting.

Error Codes The first digit will be 0, 1, 2, 3, or A. See General Errors, page Upon restarting the washer, you should be able to enter commands into the keypad. See Fatal Errors, page Page contains a partial listing of errors that may appear on the display of the ELx during operation with the Bio-Stack. For example, error code means that the microplate carrier motor x-axis could not find its optical sensor.

If auto-calibration jigs are out of calibration or incorrectly installed, the error may occur during a Dispense, Wash, or Aspirate Protocol, if plate clearance is less than priming trough clearance. Probable Causes:.

Manifold motor failed positional verify — occurs when verifying the current motor position during self-test, prior to running a program, or following a program. Carrier x-axis motor failed positional verify — occurs when verifying the current motor position during selftest, prior to running a program, or following a program. Magna models only: Carrier x-axis motor failed positional verify — occurs when verifying the current motor position during self-test, prior to running a program, or following a program.

Dual-manifold models only: Carrier y-axis motor failed positional verify — occurs when verifying the current motor position during self-test, prior to running a program, or following a program. Undefined program type - occurs when trying to define or run a program type that is invalid usually initiated from washer keypad operations. Invalid write attempt - occurs when trying to store a program in flash memory e. At that time, a checksum test is run when validating a program name, or when loading a program from flash memory to RAM.

If it fails, then the software assumes the program is corrupt in flash memory. Invalid manifold for calibration — occurs when the value stored in flash memory for the manifold type is invalid. This is checked at powerup, during self-test, and during and after autocal is run. An invalid buffer is selected — occurs when a program first starts, when fluid is going to be dispensed, or when a linked program is going to the next link.

Dispense rate is invalid for manifold type — occurs when verifying validity of a program, e. Dispense volume invalid for manifold type — occurs when verifying the validity of a program, e.

Also occurs when attempting to dispense fluid, and the transition volume for that rate is larger than the volume to be dispensed. Necessary configuration data is missing because flash memory configuration data has not been properly initialized, or flash memory is corrupted.

Failed configuration checksum test because flash memory configuration data is corrupt. Occurs during powerup, or after running a program. Manifold motor not homed successfully — occurs anytime a motor is requested to be moved before it has been homed. Some of our customers are fighting cancer. Some are fighting to maximize the efficiency, performance and economic potential of their labs. Whatever their battle, we're in it with them.

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